2024
Alkoxy Exchange Strategy for the Synthesis of N,N′-Dimethylated (Alkoxy)triazinediones as Solid Reagents for Acid-Catalyzed O-Alkylation
Hikaru Fujita, Tomomi Yagitani, Munetaka Kunishima
The Journal of Organic Chemistry 2024, in press (DOI: 10.1021/acs.joc.4c01406)
Bicyclic-Ammonium-Incorporated Ylidic Nitrogen Groups for Strong π-Electron Donation in Push–Pull Benzene π-Conjugated Systems
Hikaru Fujita, Takanari Arai, Naoto Kuchiki, Munetaka Kunishima
Organic Letters 2024, 26 (35), 7313−7317 (DOI: 10.1021/acs.orglett.4c02378)
Phototriggered Generation of Ynol Ethers and Their Rearrangement to Ketenes
Shunsuke Mogami, Masanobu Baba, Taniyuki Furuyama, Munetaka Kunishima, Kenji Mishiro
The Journal of Organic Chemistry 2024, 89 (15), 10709−10718 (DOI: 10.1021/acs.joc.4c00947)
Development of a Purely Isolable (Dimorpholino)triazine-Based Reagent for the Epoxidation of Alkenes
Hikaru Fujita, Toshiyuki Kato, Tatsuki Betsuyaku, Munetaka Kunishima
Synlett 2024, 35, in press (DOI: 10.1055/a-2356-8451)
Carbocationoids, a concept for controlling highly reactive cationic species
Hikaru Fujita, Daichi Shimada, Jotaro Kudo, Kazuyuki Kosha, Satoshi Kakuyama, Hiromitsu Terasaki, Munetaka Kunishima
Communications Chemistry 2024, 7, 55 (DOI: 10.1038/s42004-024-01139-w)
Drug–drug conjugates of MEK and Akt inhibitors for RAS-mutant cancers
Hikaru Fujita, Sachiko Arai, Hiroshi Arakawa, Kana Hamamoto, Toshiyuki Kato, Tsubasa Arai, Nanaka Nitta, Kazuki Hotta, Natsuko Hosokawa, Takako Ohbayashi, Chiaki Takahashi, Yasuhide Inokuma, Ikumi Tamai, Seiji Yano, Munetaka Kunishima, Yoshihiro Watanabe
Bioorganic & Medicinal Chemistry 2024, 102, 117674 (DOI: 10.1016/j.bmc.2024.117674)
Phototriggered Butenolide Formation from a Cyclobutenedione and an Acidic Nucleophile
Kenji Mishiro, Aiko Sesumi, Takanori Fujii, Taniyuki Furuyama, Munetaka Kunishima
Organic Letters 2024, 26 (1), 380-384 (DOI: 10.1021/acs.orglett.3c04054)
2023
Epitope-Based Specific Antibody Modifications
Saki Horie, Kenji Mishiro, Mio Nishino, Inori Domae, Mitsuo Wakasugi, Tsukasa Matsunaga, Munetaka Kunishima
Bioconjugate Chemistry 2023, 34 (11), 2022–2033 (DOI: 10.1021/acs.bioconjchem.3c00340)
Hydrophobic-Substrate-Selective Dehydrative Condensations at the Emulsion Interface under Conditions where Competitive Reactions Proceed in the Bulk Aqueous Phase
Takuya Matsumoto, Eri Hirata, Hanlin Zhang, Kazuhito Hioki, Munetaka Kunishima
Asian Journal of Organic Chemistry 2023, 12 (1), e202200602 (DOI: 10.1002/ajoc.202200602)
2022
Synthesis and characterization of tetraphenylammonium salts
Hikaru Fujita, Ozora Sasamoto, Shiori Kobayashi, Masanori Kitamura, Munetaka Kunishima
Nature Communications 2022, 13, 2537 (DOI: 10.1038/s41467-022-30282-y)
Science誌のResearch Highlightsに選ばれました！
Chem-Stationのスポットライトリサーチ(紹介ムービー付き)で紹介されました！
金沢大学プレスリリースに掲載されました！
Nucleophilic substitution reactions of unbranched alkyl amines using triazine reagents
Masanori Kitamura, Yuki Kitaoka, Hikaru Fujita, Munetaka Kunishima
Tetrahedron Letters 2022, 93, 153692 (DOI: 10.1016/j.tetlet.2022.153692)
Synthesis of N-Aminated Salts of Aliphatic tert-Amines, (Trialkyl)amidines, and (Pentaalkyl)guanidines by Electrophilic Amination in an Ethereal Solvent
Hikaru Fujita, Takanari Arai, Munetaka Kunishima
Chemical and Pharmaceutical Bulletin 2022, 70(1), 85-88 (DOI:10.1248/cpb.c21-00673)
2021
Conjugation of 4-(dimethylamino)pyridine to primary amines in aqueous buffer solutions using an N-hydroxysuccinimide ester reagent
Saki Horie, Hikaru Fujita, Rina Yamashita, Munetaka Kunishima
Tetrahedron Letters 2021, 81(28), 153343 (DOI: 10.1016/j.tetlet.2021.153343)
Development of a triazinedione-based dehydrative condensing reagent containing 4-(dimethylamino)pyridine as an acyl transfer catalyst
Jie Liu, Hikaru Fujita, Masanori Kitamura, Daichi Shimada, Munetaka Kunishima
Organic & Biomolecular Chemistry 2021, 19(21), 4712–4719 (DOI:10.1039/D1OB00450F)
A versatile iodo(III)etherification of terminal ethynylsilanes using BF3-OiPr2 and alkyl benzyl ethers
Takuya Matsumoto, Hiroshi Hagiyama, Kanetsugu Kuribayashi, Kazuhito Hioki, Hikaru Fujita, Masahito Ochiai, Munetaka Kunishima
Organic & Biomolecular Chemistry 2021, 19(17), 3825–3828 (DOI: 10.1039/D1OB00479D)
Efficiency Enhancement of a Photocatalytic Decarbonylation of an Aminocyclopropenone by Benzothiophene Substitution
Kenji Mishiro, Mitsuki Nomura, Taniyuki Furuyama, Munetaka Kunishima
The Journal of Organic Chemistry 2021, 86 (4), 3625–3636 (DOI: 10.1021/acs.joc.0c02997)
N-Acyltriazinedione; a Novel Acylating Reagent Synthesized from a Triazinone-Type Condensing Reagent
Kohei Yamada, Jeongsu Lee, Mika Kota, Yukiko Karuo, Masanori Kitamura, Munetaka Kunishima
Chemical and Pharmaceutical Bulletin 2021, 69 (5), 498–502 (DOI: 10.1248/cpb.c20-00952)
2020
6-Hydroxyindole is an endogenous long-lasting OATP1B1 inhibitor elevated in renal failure patients
Yusuke Masuo, Ken-ichi Fujita, Kenji Mishiro, Natsumi Seba, Tatsuya Kogi, Hidenori Okumura, Natsumi Matsumoto, Munetaka Kunishima, Yukio Kato
Drug Metabolism and Pharmacokinetics 2020, 35 (6), 555–562 (DOI: 10.1016/j.dmpk.2020.09.001)
Development of hydrophilic polyacrylamide gel-based condensing reagents comprised of chlorotriazine
Kohei Yamada, Shota Hirozawa, Junqing Xia, Munetaka Kunishima
Chemical and Pharmaceutical Bulletin 2020, 68 (6), 534–537 (DOI:10.1248/cpb.c20-00074)
Trizaine-based dehydrative condensation reagents bearing carbon-substituents
Masanori Kitamura, Sayaka Komine, Kohei Yamada, Munetaka Kunishima
Tetrahedron 2020, 76 (12), 130900–130912 (DOI: 10.1016/j.tet.2019.130900)
2019
Development of Triazinone-Based Condensing Reagents for Amide Formation
Kohei Yamada, Mika Kota, Kensuke Takahashi, Hikaru Fujita, Masanori Kitamura, Munetaka Kunishima
The Journal of Organic Chemistry 2019, 84 (23), 15042–15051 (DOI:10.1021/acs.joc.9b01261)
Substitution of the Dimethylamino Group in Gramines and One-Pot Cyclization to Tetrahydro-β-carbolines Using a Triazine-Based Activating Agent
Hikaru Fujita, Riho Nishikawa, Ozora Sasamoto, Masanori Kitamura, Munetaka Kunishima
The Journal of Organic Chemistry 2019, 84 (13), 8380–8391 (DOI: 10.1021/acs.joc.9b00039)
Preparation of Alkyl Ethers with Diallyltriazinedione-Type Alkylating Agents (ATTACKs-R) Under Acid Catalysis
Hikaru Fujita, Rina Yamashita, Takanori Fujii, Kohei Yamada, Masanori Kitamura, Munetaka Kunishima
European Journal of Organic Chemistry 2019, (27), 4436–4446 (DOI: 10.1002/ejoc.201900607)
Phototriggered Active Alkyne Generation from Cyclopropenones with Visible Light-Responsive Photocatalysts
Kenji Mishiro, Takeshi Kimura, Taniyuki Furuyama, Munetaka Kunishima
Organic Letters 2019, 21 (11) 4101–4105 (DOI:10.1021/acs.orglett.9b01280)
金沢大学プレスリリースに掲載されました！
Development of a Storable Triazinone-Based Reagent for O–p-Methoxybenzylation under Mild Heating Conditions
Hikaru Fujita, Hiromitsu Terasaki, Satoshi Kakuyama, Kazuhito Hioki, Munetaka Kunishima
Organic Letters 2019, 21 (9), 3093–3097 (DOI: 10.1021/acs.orglett.9b00732)
2018
Combination Metabolomics Approach for Identifying Endogenous Substrates of Carnitine/Organic Cation Transporter OCTN1
Yusuke Masuo, Yuri Ohba, Kohei Yamada, Aya Hasan Al-Shammari, Natsumi Seba, Noritaka Nakamichi, Takuo Ogihara, Munetaka Kunishima, Yukio Kato
Pharmaceutical Research 2018, 35, 224 (DOI: 10.1007/s11095-018-2507-1)
Phototriggered Ketone Formation from an Aminocyclopropenone and a Carboxylic Acid
Kenji Mishiro, Yuki Yushima, Munetaka Kunishima
The Journal of Organic Chemistry 2018, 83 (21), 13595–13603 (DOI: 10.1021/acs.joc.8b02250)
Development of triazine-based esterifying reagents containing pyridines as a nucleophilic catalyst
Kohei Yamada, Jie Liu, Munetaka Kunishima
Organic & Biomolecular Chemistry 2018, 16, 6569–6575 (DOI: 10.1039/c8ob01660g)
Cooperation of the Neutral and the Cationic Leaving Group Pathways in Acid-Catalyzed O-Benzylation of TriBOT
Hikaru Fujita , Naoko Hayakawa, Munetaka Kunishima
The Journal of Organic Chemistry 2018, 83 (17), 10684–10687 (DOI: 10.1021/acs.joc.8b01505)
Imido-substituted triazines as dehydrative condensing reagents for the chemoselective formation of amides in the presence of free hydroxy groups
Masanori Kitamura, Suguru Sasaki, Riho Nishikawa, Kohei Yamada, Munetaka Kunishima
RCS Advances 2018, 8, 22482–22489 (DOI: 10.1039/c8ra03057j)
Triazine-Based Cationic Leaving Group: Synergistic Driving Forces for Rapid Formation of Carbocation Species
Hikaru Fujita, Satoshi Kakuyama, Shuichi Fukuyoshi, Naoko Hayakawa, Akifumi Oda, Munetaka Kunishima
The Journal of Organic Chemistry 2018, 83 (8), 4568–4580 (DOI: 10.1021/acs.joc.8b00331)
Development of radioiodine-labeled acetaminophen for specific, high-contrast imaging of malignant melanoma
Wen Jing Zhu, Masato Kobayashi, Kohei Yamada, Kodai Nishi, Kotaro Takahashi, Asuka Mizutani, Ryuichi Nishii, Leo G Flores II, Naoto Shikano, Munetaka Kunishima, Keiichi Kawai
Nuclear Medicine and Biology 2018, 59, 16–21 (DOI: 10.1016/j.nucmedbio.2017.12.008)
An isolable and bench-stable epoxidizing reagent based on triazine: Triazox
Kohei Yamada, Yuki Igarashi, Tatsuki Betsuyaku, Masanori Kitamura, Koki Hirata, Kazuhito Hioki, Munetaka Kunishima
Organic Letters 2018, 20 (7), 2015–2019 (DOI: 10.1021/acs.orglett.8b00560)
化学ポータルサイトChem-Stationで紹介されました。
Development of Triazine-Based Benzylating Reagents Possessing t-Butyl Group on the Triazine Core: Thermally Controllable Reagents for the Initiation of Reaction
Yukiko Karuo, Kohei Yamada, Munetaka Kunishima
Chemical and Pharmaceutical Bulletin 2018, 66 (3), 303–308 (DOI: 10.1248/cpb.c17-00897)
Highlighted Paper selected by Editor-in-Chief
Development of highly electron-deficient and less sterically-hindered phosphine ligands possessing 1,3,5-triazinyl groups
Kazumi Abe, Masanori Kitamura, Hikaru Fujita, Munetaka Kunishima
Molecular Catalysis 2018, 445, 87–93 (DOI: 10.1016/j.mcat.2017.11.008)
2017
Novel Alkylating Reagents Designed by the Characteristics of 1,3,5-Triazines
Munetaka Kunishima, Kohei Yamada, Hikaru Fujita, Masanori Kitamura
Journal of Synthetic Organic Chemistry, Japan 2017, 75 (10), 1023–1034 (DOI: 10.5059/yukigoseikyokaishi.75.1023)
Phototriggered Dehydration Condensation Using an Aminocyclopropenone
Kenji Mishiro, Yuki Yushima, Munetaka Kunishima
Organic letters 2017, 19 (18), 4912–4915 (DOI: 10.1021/acs.orglett.7b02383)
Development of a method for the synthesis of 2,4,5-trisubstituted oxazoles composed of carboxylic acid, amino acid, and boronic acid
Yamada Kohei, Kamimura Naoto, Kunishima Munetaka
Beilstein Journal of Organic Chemistry 2017, 13, 1478–1485 (DOI: 10.3762/bjoc.13.146)
Study of O-Allylation using Triazine-based Reagents
Kohei Yamada, Naoko Hayakawa, Hikaru Fujita, Masanori Kitamura, Munetaka Kunishima
Chemical and Pharmaceutical Bulletin 2017, 65, 112–115 (DOI: 10.1248/cpb.c16-00744)
2016
N,N′-Dimethylated Benzyloxytriazinedione: A Stable Solid Reagent for Acid-Catalyzed O-Benzylation
Hikaru Fujita, Satoshi Kakuyama, Munetaka Kunishima
European Journal of Organic Chemistry 2016, (4), 833–839 (DOI: 10.1002/ejoc.201601387)
Alcohol- and Amine-Tolerant Synthesis of Six-Membered Cyclic Quaternary Ammonium Salts Using a Triazine-Based Reagent
Masanori Kitamura, Seina Yamamura, Kohei Yamada, Munetaka Kunishima
Asian Journal of Organic Chemistry 2016, 5 (12), 1508–1517 (DOI: 10.1002/ajoc.201600429)
Mild Amide-Cleavage Reaction Mediated by Electrophilic Benzylation
Kohei Yamada, Yukiko Karuo, Yuichi Tsukada, Munetaka Kunishima
Chemistry – A European Journal 2016, 22 (39), 14042–14047 (DOI: 10.1002/chem.201603120)
Development of a Triazine-based tert-Butylating Reagent, TriAT-tBu
Kohei Yamada, Naoko Hayakawa, Hikaru Fujita, Masanori Kitamura, Munetaka Kunishima
European Journal of Organic Chemistry 2016, (23), 4093–4098 (DOI: 10.1002/ejoc.201600663)
Potent triazine-based dehydrocondensing reagents substituted by an amido group
Munetaka Kunishima, Daiki Kato, Nobu Kimura, Masanori Kitamura, Kohei Yamada, Kazuhito Hioki
Beilstein Journal of Organic Chemistry 2016, 12, 1897–1903 (DOI: 10.3762/bjoc.12.179)
Development of Acid-Catalyzed Fluorous Benzylating Reagents Based on a Triazinedione Core
Munetaka Kunishima, Ryohei Asao, Kohei Yamada, Masanori Kitamura, Hikaru Fujita
Journal of Fluorine Chemistry 2016, 190, 68–74 (DOI: 10.1016/j.jfluchem.2016.09.003)
Increased Plasma Concentrations of Unbound SN-38, the Active Metabolite of Irinotecan, in Cancer Patients with Severe Renal Failure
Ken-ichi Fujita, Yusuke Masuo, Hidenori Okumura, Yusuke Watanabe, Hiromichi Suzuki, Yu Sunakawa, Ken Shimada, Kaori Kawara, Yuko Akiyama, Masanori Kitamura, Munetaka Kunishima, Yasutsuna Sasaki, Yukio Kato
Pharmaceutical Research 2016, 33 (2), 269–282 (DOI: 10.1007/s11095-015-1785-0)
2015
Study of the Reactivities of Acid-Catalyzed O-Benzylating Reagents Based on Structural Isomers of 1,3,5-Triazine
Hikaru Fujita, Naoko Hayakawa, Munetaka Kunishima
Journal of Organic Chemistry 2015, 80 (21), 11200–11205 (DOI: 10.1021/acs.joc.5b02059)
O-Benzylation of Carboxylic Acids Using 2,4,6-Tris(benzyloxy)-1,3,5-triazine (TriBOT) under Acidic or Thermal Conditions
Kohei Yamada, Saki Yoshida, Hikaru Fujita, Masanori Kitamura, Munetaka Kunishima
European Journal of Organic Chemistry 2015, (36), 7997–8002 (DOI: 10.1002/ejoc.201501172)
2014
Role of Linkers in Tertiary Amines that Mediate or Catalyze 1,3,5-Triazine-based Amide-forming Reactions
Masanori Kitamura, Fumitaka Kawasaki, Kouichi Ogawa, Shuichi Nakanishi, Hiroyuki Tanaka, Kohei Yamada, Munetaka Kunishima
The Journal of Organic Chemistry 2014, 79 (8), 3709–3714 (DOI: 10.1021/jo500376m)
Synthesis of Pyrrolidinium Salts using a Triazine-based Reagent under Mild Conditions
Masanori Kitamura, Seina Yamamura, Hiroko Kobayashi, Mariko Yamamoto, Kayo Tada, Kazuhito Hioki, Kohei Yamada, Munetaka Kunishima
Chemistry Letters 2014, 43 (10), 1593–1595 (DOI: 10.1246/cl.140503)
Development of a New Benzylating Reagent Spontaneously Releasing Benzyl Cation Equivalents at Room Temperature
Kohei Yamada, Yuichi Tsukada, Yukiko Karuo, Masanori Kitamura, Munetaka Kunishima
Chemistry – A European Journal 2014, 20 (38), 12274–12278 (DOI: 10.1002/chem.201403158)
Specific Labeling of Streptavidin for Better Understanding of Ligand Modification in Modular Method for Affinity Labeling(MoAL)
Munetaka Kunishima, Daiki Kato, Shuichi Nakanishi, Masanori Kitamura, Kohei Yamada, Keiji Terao, Tomoya Asano
Chemical and Pharmaceutical Bulletin 2014, 62 (11), 1146–1150 (DOI: 10.1248/cpb.c14-00468)
2013
A Practical Method for p-Methoxybenzylation of Hydroxy Groups Using 2,4,6-Tris(p-methoxybenzyloxy)-1,3,5-triazine (TriBOT-PM)
Kohei Yamada, Hikaru Fujita, Masanori Kitamura, Munetaka Kunishima
Synthesis 2013, 45 (21), 2989–2997 (DOI: 10.1055/s-0033-1339713)
Study of 1,3,5-Triazine-Based Catalytic Amide-Forming Reactions: Effect of Solvents and Basicity of Reactants
Munetaka Kunishima, Masanori Kitamura, Hiroyuki Tanaka, Ichiro Nakakura, Takahiro Moriya, Kazuhito Hioki
Chemical and Pharmaceutical Bulletin 2013, 61 (8), 882–886 (DOI: 10.1248/cpb.c13-00368)
Binding of sulforhodamine B to human serum albumin: A spectroscopic study
Masanori Kitamura, Koji Murakami, Kohei Yamada, Keiichi Kawai, Munetaka Kunishima
Dyes and Pigments 2013, 99, 588–593 (DOI: 10.1016/j.dyepig.2013.06.011)
A New Method Using 2-Chloro-4,6-dimethoxy-1,3,5-triazine for Facile Elimination of Dimethylamino Group in Eschenmoser’s Methylenation for Synthesis of α,β-Unsaturated Esters
Kohei Yamada, Kazumasa Masaki, Yuri Hagimoto, Seina Kamiya, Munetaka Kunishima
Tetrahedron Letters 2013, 54, 1758–1760 (DOI: 10.1016/j.tetlet.2013.01.092)
2012
Study on 1,3,5-Triazine Chemistry in Dehydrocondensation: Gauche Effect on the Generation of Active Triazinylammonium Species
Munetaka Kunishima, Takae Ujigawa, Yoshie Nagaoka, Chiho Kawachi, Kazuhito Hioki, Motoo Shiro
Chemistry – A European Journal 2012, 18, 15856–15867 (DOI: 10.1002/chem.201202236.)
A novel acid-catalyzed O-benzylating reagent with the smallest unit of imidate structure
Kohei Yamada, Hikaru Fujita, Munetaka Kunishima
Organic Letters 2012, 14 (19), 5026–5029 (DOI: 10.1021/ol302222p)
One-pot preparation of oxazol-5(4H)-ones from amino acids in aqueous solvents
Hikaru Fujita, Munetaka Kunishima
Chemical and Pharmaceutical Bulletin 2012, 60 (7), 907–912 (DOI: 10.1248/cpb.c12-00291)
N-isopropyl-p-iodoamphetamine hydrochloride is predominantly metabolized by CYP2C19
Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai, Yasutsuna Sasaki
Drug Metabolism and Disposition 2012, 40 (5), 843–846 (DOI: 10.1124/dmd.111.043893)
Substrate-selective dehydrocondensation at the interface of micelles and emulsions of common surfactants
Munetaka Kunishima, Kanako Kikuchi, Yukio Kawai, Kazuhito Hioki
Angewandte Chemie International Edition 2012, 51 (9), 2080–2083 (DOI: 10.1002/anie.201107706)
2011
New approach to oligotriazoles using a cobalt complex of propargyl azides as a synthetic component
Yuichi Tsukada, Kohei Yamada, Munetaka Kunishima
Tetrahedron Letters 2011, 52 (26), 3358–3360 (DOI: 10.1016/j.tetlet.2011.04.082)
2010
Labeling study of avidin by modular method for affinity labeling (MoAL)
Shuichi Nakanishi, Hiroyuki Tanaka, Kazuhito Hioki, Kohei Yamada, Munetaka Kunishima
Bioorganic and Medicinal Chemistry Letters 2010, 20 (23), 7050–7053 (DOI: 10.1016/j.bmcl.2010.09.109)
Effects of stereochemistry and β-substituents on the rates of vinylic SN2 reaction of hypervalent vinyl(phenyl)-λ3-iodanes with tetrabutylammonium halides
Kazunori Miyamoto, Takuji Okubo, Masaya Hirobe, Munetaka Kunishima, Masahito Ochiai
Tetrahedron 2010, 66 (31), 5819–5826 (DOI: 10.1016/j.tet.2010.04.041)
2009
Convenient modular method for affinity labeling (MoAL method) based on a catalytic amidation
Munetaka Kunishima, Shuichi Nakanishi, Jin Nishida, Hiroyuki Tanaka, Daiki Morisaki, Kazuhito Hioki, Hiroshi Nomoto
Chemical Communications 2009, (37), 5597–5599 (DOI: 10.1039/B912908A)
Synthesis of aza-bridged calix(4-methoxy)triazines toward flattened π-conjugated macrocycles
Hiroyuki Tanaka, Ayako Wada, Motoo Shiro, Kazuhito Hioki, Daiki Morisaki, and Munetaka Kunishima
Heterocycles 2009, 79, 609–616 (DOI: 10.3987/COM-08-S(D)24)
A Simple Practical Method for the Synthesis of 4,6-Dimethoxy-1,3,5-triazin-2(1H)-one Using Dimethylamine-Functionalized Solid-Phase Reagents
Kazuhito Hioki, Keiichi Ohshima, Yuko Sota, Miki Tanaka, Munetaka Kunishima
Synthesis 2009, (4), 542–544 (DOI: 10.1055/s-0028-1083330)
selected papers before 2009
Spontaneous Membrane Fusion Induced by Chemical Formation of Ceramides in a Lipid Bilayer
Munetaka Kunishima, Masafumi Tokaji, Keisuke Matsuoka, Jin Nishida, Masanori Kanamori, Kazuhito Hioki, Shohei Tani
Journal of the American Chemical Society 2006, 128 (45), 14452–14453 (DOI: 10.1021/ja0652969)
Primary-Amine-Specific Lactamization of ω-Amino Acids by an Artificial Cyclotransferase Based on [18]Crown-6
Munetaka Kunishima, Kazuhito Hioki, Takahiro Moriya, Jun Morita, Tomoko Ikuta, Shohei Tani
Angewandte Chemie International Edition 2006, 45, 1252–1255 (DOI: 10.1002/anie.200504027)
Unusual Rate Enhancement of Bimolecular Dehydrocondensation To Form Amides at the Interface of Micelles of Fatty Acid Salts
Munetaka Kunishima, Hiroko Imada, Kanako Kikuchi, Kazuhito Hioki, Jin Nishida, Shohei Tani
Angewandte Chemie International Edition 2005, 44, 7254–7257 (DOI: 10.1002/anie.200502594)
Cyclodextrin-Based Artificial Acyltransferase: Substrate-Specific Catalytic Amidation of Carboxylic Acids in Aqueous Solvent
Munetaka Kunishima, Kazuma Yoshimura, Hiroshi Morigaki, Reiko Kawamata, Keiji Terao, and Shohei Tani
Journal of the American Chemical Society 2001, 123 (43), 10760–10761 (DOI: 10.1021/ja011660m)
Formation of carboxamides by direct condensation of carboxylic acids and amines in alcohols using a new alcohol- and water-soluble condensing agent: DMT-MM
Munetaka Kunishima, Chiho Kawachi, Kazuhito Hioki, Keiji Terao, Shohei Tani
Tetrahedron 2001, 57(8), 1551–1558 (DOI: 10.1016/S0040-4020(00)01137-6)
4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methyl-morpholinium chloride: an efficient condensing agent leading to the formation of amides and esters
Munetaka Kunishima, Chiho Kawachi, Jun Monta, Keiji Terao, Fumiaki Iwasaki, Shohei Tani
Tetrahedron 1999, 55(46), 13159–13170 (DOI: 10.1016/S0040-4020(99)00809-1)
Book
2,4,6-Tris(p-methoxybenzyloxy)-1,3,5-triazine (TriBOT-PM)
Hikaru Fujita, Munetaka Kunishima
Encyclopedia of Reagents for Organic Synthesis 2021 (DOI: 10.1002/047084289X.rn02381)
4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium Chloride
Masanori Kitamura, Munetaka Kunishima
Encyclopedia of Reagents for Organic Synthesis 2013 (DOI: 10.1002/047084289X.rn01530)
Contribution
金沢大学薬学系の人材育成方針とその実現に向けた取組み
国嶋 崇隆
YAKUGAKU ZASSHI 2023, 143 (10), 821-825 (DOI: 10.1248/yakushi.23-00083-5)
有機化学者としての心得
国嶋 崇隆
有機合成化学協会誌 2022, 80(10), 897 (DOI: 10.5059/yukigoseikyokaishi.80.897)
次世代創薬科学研究者育成に向けた産学連携教育
国嶋 崇隆
MEDCHEM NEWS 2022, 31 (1), 1 (DOI: 10.14894/medchem.32.1_1)
問題解決能力
国嶋 崇隆
ファルマシア 2021, 57 (2), 81 (DOI: 10.14894/faruawpsj.57.2_81)
楽しむことの大切さを思う
国嶋 崇隆
薬奨ニュース 2021, 12, 9 (薬奨ニュースWebサイト)
